First of all how to play:
Turn 1: Sunspot or nothing (Nightcrawler only if any location helps you like Raft or Muir Island )
Turn 2: Angela or nothing (Or sunspot if you drew him)
Turn 3: Bishop or any of the other options
Turn 4: Ka-zar
Turn 5: Blue Marvel
Turn 6: Drop everything on turn 1.
Not every game is the same, but this pattern usually repeats
The only swappable cards imo are Wolfsbane and a 1 drop for another you prefer.
- You could play Iceman instead of Sunspot for an early play that disrupts opponent. I wouldn't consider Zero over him cause you need an early play.
-Armor or Captain America over Wolfsbane gives you more early plays. America Chavez over Wolfsbane sounds weird (cause you 99% of the games wont play her), but it increases your Odds of drawing Blue Marvel + Ka zar (check this video I found the other day to know the exact numbers https://www.youtube.com/watch?v=kQxVfBQCkE8))))
-Zero -> Elektra, in Pool 3 there are less 1 drops and the decks that run them usually play Armor so I could see the change.
-Cosmo should only be consider if you are facing Pool 3 decks (Wong, more counters, etc) is a good early play to protect your Ongoing cards and it counter opponent reveal plays.
-I currently don't own Mojo, but he could be a better Wolfsbane.