the main purpose of this deck is to destroy cards, as much as you can before the turn 5.
play deadpool and squirrel girl as soon as possible and destroy them with carnage, killmonger and deathlock (venom) when you have a chance. same with bucky and wolverine. (using yondu or nova like a support).
the best scenario is to arrive to the turn 5 and skip it playing nothing, with already 9 "things" destroyed (also enemies cards are counted so you can wisely use killmonger after they play some "1 cost" card or after some location that add "squirrel", "raptors" or "stones"). at that moment if you're lucky and you have she hulk, captain marvel and death in your hands, at the last turn you can play all of them 5 (captain marvel) 1 (she hulk, after you skipped the previous turn) and 0 (death, after your destroying move).
in case of emergency, you can have deadpool with attack rised and bucky transformed.