Negatively Nimrod - Nimrod x Knull x Negative

Try to get Negative out as early as possible with Zabu or Psylocke. 

Use your destroy cards to proc the Nimrod and make your Knull bigger. If Knull or Zola is Negative when you draw them then you can use Zola on the Knull to double Knull's stats. Zola on Iron Man can be good too.