Draw Disruption

Works well against:

Combo decks: Stops your opponent from getting key cards

Discard decks: Disrupts all discard consistency, and Colleen Wing. Although, this does feed Morbius / Modok.

Cerebro decks (Low-power variants): Reduces amount of cards able to be played, as well as number drawn

Lockjaw decks: Not too sure about this, but extra rocks in deck should mess up consistency, as well as low plays-per-turn

Strong Guy: Consistent 1-card minimum hand

Works poorly against:

Patriot decks: Gives your opponent rocks

Spam decks: Provides spammable cards

Collector / Quinjet decks: Provides your opponent cards not originally from their deck

Electro decks: They're only using one card a turn anyway

Devil Dinosaur: Big hand