I've earned 10 Infinity conquest tickets with this deck so far, it's been my best performing deck for me even in spite of the recent Angela/Elsa nerf, and I'd strongly recommend running it if you want to earn tickets quickly and securely.
Basic strategy: Get a lane huge early, play Magik, then lock down your winning lane with Professor X. After that, win the 2nd lane with (T6 Alioth -> T7 Odin), (Gamora -> Odin), (Gamora -> Alioth), or (Alioth -> Gamora).
Ideally you want Alioth into Odin as it's the most reliable but there are other options if you miss the draw. You can also play an extra Nebula or Nico on t7 for a small boost in power as well.
Gamora can be swapped out with Spider-Woman if you're worried about Shang Chi, but keep in mind Shang Chi can be countered by Alioth the turn after if you have turn priority. Spider-woman feels weak right now due to how popular Luke Cage currently is, but your mileage may vary.
Nico is a very versatile card here. She can be used on T7 for an extra boost (or T6 with Gamora), she gets you closer to Elsa's bonus since she's a cheap card, and her being able to buff or duplicate Jeff is very strong as well. Her draw 2 spell is also great if you really want to draw out your win condition early, ideally this should be used on Magik, but any card should be fine for it. If you don't have Nico you can try running Kitty instead, as this is what I did pre-nerf, but honestly I just don't think Kitty is worth it in this deck, she doesn't benefit Angela/Elsa nearly as much as before.
Elsa is here so that we can ideally buff Jeff to a 2/5 and move him around as needed. Useful in games where you need to guess where Professor X will work in case Daredevil wasn't drawn in time. We can also get a 2/5 Jeff after Professor X has been played by playing Jeff as the 4th card into that lane, which can be useful.
Angela should be played into the lane you want to lock down if possible. Angela and Elsa will usually end up at least 2/4 in value so they are still very worth using despite their recent nerfs. If you're missing Elsa you should be able to get similar results using Forge, although this weakens you to possible Killmonger plays.
We run a Shang Chi in this deck so that we can pull out surprise wins vs Shuri/Sauron/Venom users, otherwise we just can't beat those decks as they will overpower us.
Armor counters us pretty hard, so if you see an armor, either try and win the lane with professor X, or try to win somewhere else. You can still win this lane later with Gamora alone, or Gamora -> Odin, but it's riskier than just securing it with Alioth. Similar logic applies to Cosmo. We can also lose to enemy Alioths if we don't have priority so be careful of that as well.
Also be careful of your opponent buffing the locked-down lane with cerebro/surfer/spectrum/tribunal/jeff/klaw/mr. fantastic as well. You can often shut this down with Alioth before it happens but this will vary game-by-game.