A Jean Grey deck I have been having a lot of success with at relatively high infinite. Gained about 75 cubes with a 58.2% winrate up to around rank #1500. Here is how to play the deck.
Turn 1: Play The Hood on right lane if you have him. Otherwise Nebula left lane or mid, or Nightcrawler mid. The idea is to play Nightcrawler on the lane you plan to Jean Grey, Nebula on a lane you will not play Jean Grey on. The Hood right lane in order to setup an Annihilus play to win right lane.
Turn 2: Play Jeff mid or the Demon/Another 1 drop as you would play them if it were turn 1.
Turn 3: Jean Grey mid lane preferably. If mid is not available then left lane with right lane as the last resort. If not Jean Grey then Gladiator or Shanna is fine provided that Shanna does not fill up the lane where you play her.
Turn 4: Sentry on the Jean Grey lane, otherwise Shanna on the Jean Grey lane IF you already have a mover(Nightcrawler/Jeff) on the Jean Grey lane. You don't want to fill the Jean Grey lane without a mover there for late flexibility. If you have a mover on the Jean Grey lane then fill it up ASAP.
Turn 5: Annihilus on the Jean Grey lane or on left/right if the Jean lane is full. If no Annihilus then Vision on the Jean Grey lane.
Turn 6: Alioth where needed.
The idea of the deck is to restrict where your opponent can play while giving yourself flexibility with movers who can go where needed. Shanna and Annihilus project power into other lanes, Stegron can do some tricky plays to win games, and Gladiator helps fight for priority in order to setup Alioth plays on turn 6. Jean Grey restricts the options that the opponent has for dealing with Sentry/Annihilus. It's rare to see Jean Grey so noone really knows what to expect in a Jean Grey deck. This means you can snap before playing Alioth and it gets paid off a lot.