This is a pretty straightforward Lockjaw deck except for the added bonus of Madame Web.
I personally run Giganto instead of Doctor Doom because of the Madame Web , however Doom works very well in this deck as he does other Lockjaw decks.
I opted for Iceman and Scorpion because I feel as if they both have good cycle effects, however cards are gonna be bouncing in and out of your deck with Lockjaw, which can make huge numbers with cards such as Rocket Racoon, Silver Sable, etc.
I imagine Jane and Beta Ray Bill would work lovely in this deck, but I don't have them yet. They would be a good swap out for Iceman and Scorpion if you don't want them.
I ran Baron Zemo in this deck for a little while and he worked out surprisingly well, especially with the Madame Web bonus of being able to move.