Mega Clog

yellow jacket, hazmat, man thing and typhoid mary bring down the power of mysterio's illusions and debri's rocks into annilus range to send over and clog opponent. yellow jacket played on turn 5 paired with annilus. 

Assuming you have priority, ideal turn 6 would be cosmo and luke cage. cosmo is used to counter opponents annilus. luke cage mostly played late game to counter any self inflicted negative power caused by typhoid mary or hazmat.